Saturday, February 11th, 2012
Research and Markets (http://www.researchandmarkets.com/research/16399d/exploring_the_epig) has announced the addition of the "Exploring the Epigenetics Market: Opportunities for Product Placement and Innovations" report to their offering.
Over the past five years or so renewed attention has been paid to the field of epigenetics as scientists piece together a molecular puzzle revealing how heritable information, other than the DNA itself influences gene function. DNA methylation, histone modifications and chromatin structures all play a central role in the regulation and expression of mammalian genomes and are the central focus of much research today. Breakthroughs in epigenetics have also increased our understanding of transcriptional regulation, nuclear organization, embryonic development, and disease states. These insights will also be critical for advancing any field rooted in genetics including pharmacogenomics, stem cells, cloning, development, aging, and synthetic biology. Furthermore, as more epigenetic markers are associated with specific diseases, tools can be developed to diagnose patients and gauge the severity of disease.
Based upon a survey of 200 scientists, Exploring the Epigenetics Market: Opportunities for Product Placement and Innovations presents findings from a study that benchmarks the state of basic epigenetic research. While epigenetics research can employ such commonplace molecular biological techniques as restriction enzyme digestion, primer extension and Southern blotting, it also involves more complex technologies as DNA sequencing, PCR, real-time PCR, HPLC, and MALDI-TOF MS. Advances enabling faster and cheaper mapping of epigenetic modifications have accelerated discoveries in the field. This report reviews progress in both the discovery of epigenetic markers and the development of new epigenetics-based tools, and highlights opportunities for suppliers interested in designing and manufacturing new technologies to support epigenetics researchers.
In this study, scientists elaborate on processes and techniques they use to do epigenetics research, problems with protocols and antibodies, changes expected in the time/effort devoted to epigenetics research over the next couple of years and the estimated change in spending on chIP-related consumables through 2011. Scientists also provide opinions about suppliers of chIP and non-chIP grade antibodies, and indicate how these products are used, satisfaction with suppliers and desired improvements with each.
Designed to provide guidance for life science suppliers selling products that support epigenetic research involving chromosome immunoprecipitation (chIP), Exploring the Epigenetics Market: Opportunities for Product Placement and Innovations will help suppliers optimize product offerings and strengthen market position.
The goal of this study is to provide life science suppliers selling products that support epigenetic research conducted using chromosome immunoprecipitation (chIP) with information1 on how best to optimize their product offerings and strengthen their market position by identifying:
? Processes and techniques scientists use to study epigenetics correlated with research goals
? Anticipated change in percent of time/effort devoted to epigenetics research over the next several years
? Key sources of information (i.e., scientific journals and conferences) that epigenetics researchers use to stay abreast of their field
? Comparison of 2008 and 2009 expenditures on chIP consumables
? Throughput and multiplex expectations for chIP assays
? Prevalence of chIP kits and chIP-grade antibodies versus "do it yourself" chIP assays and researcher-validated antibodies for chIP assays
? Leading suppliers of chIP assay kits and chIP-grade antibodies
? Critical problems with chIP protocols and antibodies and the prioritization of specific improvements
? Species, clonality, and target requirements for chIP-grade antibodies
? Suppliers of non chIP-grade antibodies used in chIP assays
? Validation issues associated with non chIP-grade antibodies
? Comparison of chIP-Chip and chIP-Seq techniques
? Degree of interest in conducting whole genome analysis studies
? Leading suppliers of chIP-Chip arrays and chIP-Seq systems
Key Topics Covered:
Section 1. Key Findings & Implications
Introduction
in-Depth Analysis
Summary
Section 2. Methodology & Demographics
Section 3. Presentation of the Survey Data
Overview of Epigenetics Resesarch
Experience with Chromosome Immunoprecipitation Assays for Epigenetics Research
Experience with Chromosome Immunoprecipitation Antibodies for Epigenetics Research
Special Focus on Chip-Grade Antibodies
Special Focus on Non Chip-Grade Antibodies
Laboratory Budget for Epigenetics Research
Special Focus on Chip-Chip Experiments
Level of Involvement in Epigenetics Field
For more information visit http://www.researchandmarkets.com/research/16399d/exploring_the_epig
